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Trophoblast stem cell
Real pictures of the trophoblast stem cell delivered by gather.site, each with its paper.
4 pictures and 4 papers.
Gallery
Representative brightfield images of day 4 structures, showing the effects of N2B27, 2% DMSO, and PDA83 conditions on cyst formation in SC9N. Scale bar, 400 µm. (human (SC9N stem cells); Fig. 1, panel b (brightfield day 4 structures, cyst formation; rows mid-section of figure).)
Alsolami, Chandrasekaran, Jin et al 2026, Cell Research · CC BY 4.0
Ultrastructure of CTB and STB in trophoblast organoids. (A) Scanning electron microscopy (SEM) images of STB organoids reveals a topography of microvilli (scale bar 100 μm, inset scale bar 10 μm). (B) TEM of STB shows microvilli and syncytiotrophoblast ultrastructure; (C) TEM of cytotrophoblast (CTB) shows organelle-rich cytoplasm. Derived from human trophoblast stem cells (CT27 line). (human (trophoblast stem cell line CT27); Figure 2, A-C.)
Zhou J et al 2025, iScience · CC BY 4.0
Immunofluorescence of human HNES1-derived blastoid at 96 h of culture, stained for OCT4 (cyan, inner cell mass), GATA3 (green, trophectoderm), LEF1 (magenta), and SOX17 (grey, hypoblast). The GATA3-positive outer layer identifies trophectoderm cells. Scale bars shown. (human (HNES1-derived blastoid model); Figure 4, A.)
Ross C et al. 2025, Journal of cell science · CC BY 4.0
Immunofluorescence of human trophoblast stem cells (hTSCs) showing trophectoderm lineage markers. Control (Ctrl) and CDX2-overexpressing hTSCs stained for trophoblast identity markers. Scale bars 100 μm. hTSCs serve as a proliferating trophectoderm model maintaining CDX2 expression. (Homo sapiens; Figure 3.)
Rong L 2024, Cell proliferation · CC BY 4.0
Papers
- Alsolami S, Chandrasekaran AP, Jin Y, Wang Y, Zhang L, Shakir IM, et al. A single small molecule-based human embryo model reveals V-ATPase requirement in mammalian blastocyst cavitation. Cell Res. 2026;36:475-498. PMID: 41936702.
- Ross C, Balestrini PA, Bates LE, Azami T, Adakole T, Semple M, et al. WNT-mediating TCF/LEF transcription factor gene expression in early human pluripotency and cell lineages differs from the rodent paradigm. J Cell Sci. 2025;138:jcs264257. PMID: 40844425.
- Zhou J, Sheridan MA, Tian Y, Dahlgren KJ, Messler M, Peng T, et al. Development of apical out trophoblast stem cell derived organoids to model early human pregnancy. iScience. 2025;28:112099. PMID: 40129708.
- Rong L, Xiang L, Ai Z, Niu B, Wang Y, Yin Y, et al. The impact of dynamic caudal type homeobox 2 expression on the differentiation of human trophoblast lineage during implantation. Cell Prolif. 2024;57:e13729. PMID: 39161168.