Literature / Library / Synoviocyte
Synoviocyte
Real pictures of the synoviocyte delivered by gather.site, each with its paper.
3 pictures and 3 papers.
Gallery
Fluorescence microscopy showing cytoskeletal remodeling in human RA fibroblast-like synoviocytes (RA-FLS) treated with triptolide. Cytoskeletal staining reveals the actin network and morphological changes in synoviocytes isolated from rheumatoid arthritis patients. (human (RA synovial fibroblasts, rheumatoid arthritis); Figure 3, A.)
Shen J et al. 2025, Frontiers in pharmacology · CC BY 4.0
Immunohistochemical analysis of polarization markers in the intimal lining layer (ILL) of synovial tissue from spondyloarthritis (SpA) and rheumatoid arthritis (RA) patients. Expression of CD68, CD163, and CD32 in the ILL (panels A-C), showing macrophage-like synoviocytes (type A synoviocytes) lining the joint space. (human (synovial tissue, RA and SpA patients); Figure 2.)
Ambarus CA et al. 2012, Arthritis research & therapy · CC BY 4.0
Haematoxylin and eosin (H&E)-stained sections of human synovial tissue from control (normal) hip and hip osteoarthritis (HOA). The control synovial membrane (left panels) shows a thin intima consisting of 1 to 3 layers of fibroblast-like synoviocytes (type B synoviocytes) overlying a loose sublining stroma. In osteoarthritis (right panels), the intima is thickened with increased synoviocyte layers and subintimal cellular infiltrates. Low and high magnification panels shown. (human (hip joint synovium); Figure 2, a-f.)
Todorovic P et al. 2025, Biomedicines · CC BY 4.0
Papers
- Todorović P, Jurić I, Kelam N, Rošin M, Čarić D, Boban D, et al. Immunohistochemical Expression of TNFR1, IL-6, and TGF-β1 in the Synovial Tissue of Patients with Hip Osteoarthritis. Biomedicines. 2025;13:2732. PMID: 41301825.
- Shen J, Fang Y, Xu N, Chen H, Zhu M, Li D, et al. Exploring the mechanism of triptolide inhibiting the motility of fibroblast-like synoviocytes in rheumatoid arthritis via RhoA/Rho-associated kinase axis, based on network pharmacology, molecular docking and molecular dynamics simulations. Front Pharmacol. 2025;16:1545514. PMID: 40248103.
- Ambarus CA, Noordenbos T, de Hair MJ, Tak PP, Baeten DL. Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis. Arthritis Res Ther. 2012;14:R74. PMID: 22494514.