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Plantar skin

Real pictures of the plantar skin delivered by gather.site, each with its paper.

3 pictures and 3 papers.

Gallery

H&E-stained sections showing the morphological differences between plantar skin (left) and nonplantar skin (right). Plantar skin has a notably thicker stratum corneum (SC) and viable epidermis (VE) compared to nonplantar skin. Human ex vivo skin biopsies. (human; Figure 2, A.)

Boyle CJ et al. 2019, Science advances · CC BY 4.0

Immunohistochemical and immunofluorescence detection of selected mechanosensitive ion channel-related proteins (Piezo1, Piezo2, TRAAK) in Meissner corpuscles of human glabrous skin. Meissner corpuscles — encapsulated mechanoreceptors in the dermal papillae of plantar and palmar skin — show immunoreactivity for ion channel proteins. Note the characteristic elongated lamellated structure of each corpuscle. (Homo sapiens; Figure 1.)

Amigo I 2026, International journal of molecular sciences · CC BY 4.0

Volar characteristics recapitulated in ectopic graft sites. Masson's trichrome-stained volar MSTC (microcolumn skin tissue constructs) graft tissue sections at various timepoints after engraftment, demonstrating persistent volar characteristics including a thickened stratum corneum, acanthotic epidermis and collagen-rich dermis. Panels show how volar (plantar) skin structure with its characteristic thick epidermis and dense collagen bundles compares to non-volar skin. (Homo sapiens; Figure 4.)

Fuchs C 2024, FASEB journal : official publication of the Federation of American Societies for Experimental Biology · CC BY 4.0

Papers

  1. Amigo I, García-Mesa Y, Cuendias P, Feito J, García-Suárez O, Abreu-Velez AM, et al. Exploratory Immunohistochemical Mapping of Mechanosensitivity-Associated Ion Channel Proteins in Terminal Glial Cells of Human Meissner and Pacinian Corpuscles. Int J Mol Sci. 2026;27:6525. PMID: 42511862.
  2. Fuchs C, Wang Y, Wise E, Farinelli WA, Anderson RR, Cho S, et al. Structural and molecular characteristics of weight-bearing volar skin can be reconstituted by micro skin tissue column grafting. FASEB J. 2024;38:e23873. PMID: 39105468.
  3. Boyle CJ, Plotczyk M, Villalta SF, Patel S, Hettiaratchy S, Masouros SD, et al. Morphology and composition play distinct and complementary roles in the tolerance of plantar skin to mechanical load. Sci Adv. 2019;5:eaay0244. PMID: 31633031.

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