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Pituitary endocrine cell

Real pictures of the pituitary delivered by gather.site, each with its paper.

3 pictures and 2 papers.

Gallery

Plurihormonal pituitary adenoma with trabecular structure, hematoxylin and eosin stain ×100. Pituitary adenoma cells are arranged in trabecular cords with minimal stroma. These cells closely resemble normal anterior pituitary cells (somatotrophs, corticotrophs, gonadotrophs) from which they derive. (human (anterior pituitary adenoma, plurihormonal); Figure 1.)

Mitrofanova LB et al. 2019, Oncotarget · CC BY 4.0

Double stain immunohistochemistry, normal anterior pituitary, Growth hormone/NeuroD1, x400. Growth hormone (somatotrophs) is visualized in red, NeuroD1 in blue. Shows the normal spatial organization and morphology of anterior pituitary cells. (human (normal anterior pituitary, surgical specimen adjacent to adenoma); Figure 16.)

Mitrofanova LB et al. 2019, Oncotarget · CC BY 4.0

H&E stain at ×260 original magnification showing partly exfoliated cuboidal epithelial cells of a Rathke's cleft cyst and adjacent normal anterior pituitary tissue. The anterior pituitary (adenohypophysis) parenchyma comprises acidophilic cells (somatotrophs producing GH, and lactotrophs producing PRL, staining pink-red), basophilic cells (corticotrophs, thyrotrophs, and gonadotrophs, staining blue-purple), and pale chromophobe cells arranged in organoid nests separated by sinusoidal capillaries. (human (anterior pituitary, surgical specimen); Figure 5.)

Hacioglu A et al. 2025, Reviews in endocrine & metabolic disorde · CC BY 4.0

Papers

  1. Hacioglu A, Tekiner H, Altinoz MA, Ekinci G, Bonneville JF, Yaltirik K, et al. Rathke's cleft cyst: From history to molecular genetics. Rev Endocr Metab Disord. 2025;26:229-260. PMID: 39939491.
  2. Mitrofanova LB, Vorobeva OM, Gorshkov AN. Analysis of pituitary adenoma expression patterns suggests a potential role for the NeuroD1 transcription factor in neuroendocrine tumor-targeting therapies. Oncotarget. 2019;10:289-312. PMID: 30719226.

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