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Nephron progenitor (cap mesenchyme)
Real pictures of the nephron progenitor (cap mesenchyme) delivered by gather.site, each with its paper.
2 pictures and 2 papers.
Gallery
Immunofluorescence images of human iPSC-derived metanephric mesenchyme nephron progenitor cells on day 9 of kidney organoid differentiation. Cells stained for MM markers: SIX2 (green) and PAX2 (red). Scale bar 1000 μm. Shows nephron progenitor cells co-expressing SIX2 and PAX2, key transcription factors of the cap mesenchyme. (human (iPSC-derived metanephric mesenchyme, nephron progenitor stage day 9); Figure 6, b.)
Kearney H et al. 2025, Stem cell reviews and reports · CC BY 4.0
Immunohistochemical staining for stem cell markers in human fetal kidney (HFK) at 12, 13 and 18 weeks of gestation. Panel includes SIX2, NCAM1, FZD7, ACVR2B and NTRK2 staining in paraffin-embedded kidney sections. SIX2+ cells mark the cap mesenchyme (nephron progenitor population) in the developing metanephric mesenchyme. (human (fetal kidney 12-18 weeks gestation); Figure 3, a.)
Metsuyanim S et al. 2009, PloS one · CC BY 4.0
Papers
- Kearney H, Rak-Raszewska A, Seijas-Gamardo A, Escarda-Castro E, Caiment F, Wieringa P, et al. Dimethyl Sulfoxide Conditions Induced Pluripotent Stem Cells for more Efficient Nephron Progenitor and Kidney Organoid Differentiation. Stem Cell Rev Rep. 2025;21:2745-2764. PMID: 40965814.
- Metsuyanim S, Harari-Steinberg O, Buzhor E, Omer D, Pode-Shakked N, Ben-Hur H, et al. Expression of stem cell markers in the human fetal kidney. PLoS One. 2009;4:e6709. PMID: 19696931.