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MII oocyte
2 pictures and 2 papers.
Gallery
Representative bright-field (A-D) and birefringence (A1-D1) images of metaphase II spindle-positive oocytes captured using the Oosight Imaging System. Oocytes were qualitatively classified on the basis of birefringence morphology and signal intensity in both the spindle and zona pellucida (ZP). (human; Figure 1, panels A-D (bright-field) and A1-D1 (birefringence), four quality groups of human MII oocytes.)
Lee, Chen, Lo et al 2026, Frontiers in Endocrinology · CC BY 4.0
Cytoplasmic reorganisation of oocytes treated or not with metaphase II-follicular fluid extracellular vesicles (MII-ffEVs) during in vitro maturation. TEM images of oocytes. Scale bars (A-C) 20 µm, (D) 10 µm and (E-H) 5 µm. M-SER, mitochondria smooth endoplasmic reticulum (highlighted by white dotted line); MV, mitochondria vesicle; pvs, perivitelline space; mi, microvilli; ZP, zona pellucida. (human; Figure 5, panels A-C (whole-oocyte TEM at 20 µm scale; rows 0-707 of figure).)
Makieva, Saenz-de-Juano, Almiñana et al 2026, Human Reproduction Open · CC BY 4.0
Papers
- Lee CI, Chen HH, Lo WC, Huang CC, Lee TH, Lin PY, et al. Spindle-to-oocyte light retardance ratio as a noninvasive biomarker for oocyte quality assessment: a prospective cohort study. Front Endocrinol (Lausanne). 2026;17:1803476. PMID: 42165024.
- Makieva S, Saenz-de-Juano MD, Almiñana C, Bauersachs S, Bernal-Ulloa S, Xie M, et al. Treatment of human oocytes with extracellular vesicles from follicular fluid during rescue in vitro maturation enhances maturation rates and modulates oocyte proteome and ultrastructure. Hum Reprod Open. 2026;2026:hoag021. PMID: 41924634.