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Leptocyte (target cell)
Real pictures of the leptocyte (target cell) delivered by gather.site, each with its paper.
2 pictures and 2 papers.
Gallery
Peripheral blood smear at 1000x magnification with Giemsa staining showing target cells (codocytes) in a patient with heterozygous hemoglobin C (HbC) disease. Target cells are characterized by a central dense disc surrounded by a pale ring and an outer dense rim. (human (peripheral blood, heterozygous hemoglobin C disease); Figure 1.)
Hamidine M et al. 2026, Cureus · CC BY 4.0
Peripheral blood smear (x1000 magnification) in hemoglobin sickle-beta-thalassemia showing target cells (codocytes), sickle cells, and hypochromic microcytes. Target cells are characterised by a central dense area (bullseye), pale ring, and dense outer rim, formed by excess membrane relative to intracellular haemoglobin. (human (peripheral blood, hemoglobin sickle-beta-thalassemia); Figure 3.)
Tokuno H et al. 2025, Cureus · CC BY 4.0
Papers
- Hamidine M, Awati M, Mehdi A. Beyond Iron Deficiency: An Atypical Peripheral Smear Revealing Hemoglobin C in an Adolescent. Cureus. 2026;18:e104722. PMID: 41939689.
- Tokuno H, Ishizuka K, Seki T, Kosaka S. Hemoglobin Sickle-Beta-Thalassemia With an Acute Crisis. Cureus. 2025;17:e86078. PMID: 40666551.