Literature / Library / Kidney
Kidney
Real pictures of the kidney delivered by gather.site, each with its paper.
6 pictures and 4 papers.
Gallery
A: The glomerulus reveals a normal histology with delicate capillary walls and normal cellularity. (PAS; Magnification ×230). B: The electron microscopy shows diffuse effacement of the foot processes of the glomerular epithelial cells or podocytes with microvillous changes of the cell surface (Original magnification on the EM image, ×6,000). C: The immunofluorescence microscopy shows fine dusting of IgG deposited over the podocytes and along the glomerular capillary walls (FITC-labelled anti-IgG; Magnification ×345). (human (kidney biopsy, glomerulus); Figure 1, full figure (panels A–E).)
Alhaddad et al. 2025, Clinical Nephrology Case Studies · CC BY 4.0
H&E stain of human renal allograft biopsy showing a glomerulus with thickened capillary walls and increased mesangial matrix (transplant glomerulopathy with C4d staining). The glomerular architecture clearly shows capillary loops, podocytes, mesangial cells, and Bowman's space. (human (renal allograft biopsy); Figure 1, A.)
Chutani A et al. 2024, Transplant international : official journal of the European Society for Organ Transplantation · CC BY 4.0
Segmentation visualisations of glomeruli in major glomerular injury patterns from PAS-stained human kidney biopsies. Representative images from the internal AC_B cohort showing glomeruli with varying injury patterns. The glomerular architecture shows capillary tuft, mesangial matrix, podocytes, and Bowman's capsule. Automated glomerular instance segmentation overlay shown in color. (Homo sapiens; Figure 1.)
Hölscher DL 2023, Nature communications · CC BY 4.0
Immunofluorescence of human proximal tubule cells from a brain-dead donor kidney. Megalin (LRP2, a proximal tubule brush-border multi-ligand receptor) co-localizes with AQP1 (water channel of the apical brush border) at the apical membrane. Human donor kidney tissue showing normal proximal tubule architecture with apical marker co-expression. (Homo sapiens; Figure 2.)
Aomura D 2026, Physiological reports · CC BY 4.0
Segmentation visualisations of tubules with large variation in size and shape in various diseases and morphological injury patterns. PAS-stained human kidney biopsy patches from the internal AC_B cohort (1043 patient biopsies). Proximal and distal tubules are visible with their characteristic epithelial cell morphology, including the brush border of proximal tubule cells. Automated tubule instance segmentation overlay shown in color. (Homo sapiens; Figure 2.)
Hölscher DL 2023, Nature communications · CC BY 4.0
VCAM1 (vascular cell adhesion molecule 1) immunohistochemistry in human donor kidney tissue. VCAM1 expression is detected in proximal tubule cells from donors with varying degrees of kidney injury. Proximal tubule architecture with epithelial cells lining the tubular lumen is shown. Human brain-dead donor kidney biopsy. (Homo sapiens; Figure 4.)
Aomura D 2026, Physiological reports · CC BY 4.0
Papers
- Aomura D, Burfeind KG, Funahashi Y, Groat T, Munhall AC, Malinoski DJ, et al. Isolation and functional characterization of primary human proximal tubular epithelial cells from brain-dead organ donors. Physiol Rep. 2026;14:e70963. PMID: 42237698.
- Alhaddad J, Allos H, Dimitrov D, Nader CM, Rennke HG, Jaber BL. Minimal change disease in treatment-naïve hepatitis C virus infection: A case report and literature review. Clin Nephrol Case Stud. 2025;13:1-7. PMID: 39816676.
- Chutani A, Guevara-Pineda D, Lerner GB, Menon MC. Re-Evaluating the Transplant Glomerulopathy Lesion-Beyond Donor-Specific Antibodies. Transpl Int. 2024;37:13365. PMID: 39640250.
- Hölscher DL, Bouteldja N, Joodaki M, Russo ML, Lan YC, Sadr AV, et al. Next-Generation Morphometry for pathomics-data mining in histopathology. Nat Commun. 2023;14:470. PMID: 36709324.